OHDSI Home | Forums | Wiki | Github

Trying Again with Acute Liver Failure Due to Acute EmailFailure

Researchers
#1

Hi Christian,

And now that I think about it portal hypertension not uncommon in acute severe liver disease without failure as well as chronic liver disease.

In any event ould not be a good criteria in any event by itself.

Still wonder if acute-on-chronic (i.e. acute decompensation) of cirrhosis might be ccontained in one of the numerous concept mappings to acute liver failure.

I am replying as new post because I seem to be making an error by just replying to the email. I get messages that I made an error and reply has not content.

Thanks

Manfred

#2

@hergchan:

You can just reply to the email. Wiki will put it in correctly. The only thing is you can’t easily use the formatting, therefore I usually don’t do it that way.

The problem with the acute liver failure is that we really don’t know the pathogenesis of that effect. And we don’t know (or I don’t know) whether a drug-induced liver failure may happen as an acute on chronic effect, it probably can. The reason folks focus so much on the acute-out-of-the-blue one is that it can be devastating: It gets a lot of attention when a patient with no prior damage to the liver suddenly develops a fulminant liver failure, sometimes resulting in the need for a transplantation or death.

#3

Yes-acute liver failure is one of the classic designated medical events (DMEs)-always on the worst first list.

Thanks

t