Registry-based randomised controlled trials

Dear OHDSI Community,
I am currently exploring the feasibility of using OHDSI tools to design and conduct Randomized Registry Clinical Trials (RRCTs). The idea of leveraging real-world data to conduct these types of trials is incredibly appealing, as it combines the rigor of randomization with the generalizability and efficiency of real-world evidence.

I would like to know if there are any examples or case studies within the OHDSI community where RRCTs have been conducted using OHDSI tools or similar methodologies.

If you have any insights, resources, or relevant experiences, I would greatly appreciate your input. I am excited about the possibility of contributing to the OHDSI community’s growing body of knowledge and would love to collaborate with others interested in this topic.

Looking forward to hearing your thoughts!

Best regards,
João Silva