Wanted everyone to see we had a plug for OHDSI in our recent Open Letter communication from The Bill & Melinda Gates Foundation, authors from Wellcome Trust and Gates.
this is the section:
To help establish standardized clinical endpoints and case definitions that help regulators and policy makers evaluate data and make decisions, current efforts have accelerated to develop a standard approach to convert clinical trial data to the most commonly used observational, real world evidence data models. For example, the Observational Health Data Science & Informatics (OHDSI) open science consortium is refining a US National Institute of Health approach to migrate data from the standard Clinical Data Interchange Standards Consortium (CDISC) Study Data Tabulation Model (SDTM) format to the OHDSI Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM)16,17. Global experts and implementers abound, and sustainability is strong—these are the most widely used standards globally for formatting trial data and storing observational data18–20. Wide adoption of one of these standards enabled one study to compile a virtual real-world evidence dataset with over 300,000 users of hydroxychloroquine in combination with azithromycin21. Likewise, wide adoption of, for example, the same inclusion/exclusion criteria and primary endpoints could enable clinical or implementation science researchers to compile a systematic review with compelling evidence.
So glad to highlight OHDSI!!