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Lung Cancer Stage IA3


(JD Liddil) #1

So I have Stage IA3 for Lung Cancer.

I don’t seem to be able to find it in any vocabularies. Suggestions?

JD


(Christian Reich) #2

You will very soon, @jliddil1. We are finalizing the release of the cancer attribute vocabularies. We’ll roll it out properly.


(JD Liddil) #3

cool thanks


(Michael Gurley) #4

It looks like IA3 is an ‘Overall Stage’ derived from a particular combination of T and N and M for Lung Cancer. A particular combination that depends on a new T possible value introduced in AJCC/UICC 8 edition: T1c. See here for reference:

https://www.jtcvs.org/article/S0022-5223(17)32136-0/pdf.

The OMOP Oncology CDM extension is targeting to make NAACCR/SEER the standard OMOP oncology diagnosis modifier vocabulary. However, currently, we can only obtain UICC 7th edition TNM values for the following NAACCR variables:

TNM CLIN T NAACCR 940
TNM CLIN N NAACCR 950
TNM CLIN M NAACCR 960

AJCC TNM CLIN T NAACCR 1001
AJCC TNM CLIN N NAACCR 1002
AJCC TNM CLIN M NAACCR 1003

TNM PATH T NAACCR 880
TNM PATH N NAACCR 890
TNM PATH M NAACCR 900

AJCC TNM PATH T NAACCR 1011
AJCC TNM PATH N NAACCR 1012
AJCC TNM PATH M NAACCR 1013

See here for the values we will be pulling for Clinical T/Pathological T/TNM Stage Group for Lung Cancer:

https://staging.seer.cancer.gov/tnm/input/1.9/lung/clin_t/?breadcrumbs=(~schema_list~),(~view_schema~,~lung~)

https://staging.seer.cancer.gov/tnm/input/1.9/lung/path_t/?breadcrumbs=(~schema_list~),(~view_schema~,~lung~)

https://staging.seer.cancer.gov/tnm/input/1.9/lung/clin_stage_group_direct/?breadcrumbs=(~schema_list~),(~view_schema~,~lung~)

So that would mean even with the ingestion of NAACCR/SEER into the OMOP vocabulary, ‘IA3’ would not be supported. Thanks for catching this. We will have to push for a way to obtain AJCC/UICC 8th edition for NAACCR/SEER variables.

Also, in general, if you have a lot of oncology diagnosis modifier use cases, could you please begin assessing how well NAACCR/SEER will be able to handle them?


(JD Liddil) #5

We use only NAACCR, AJCC, SEER terms so if OMOP pulled int he latest versions we would be good to go for the most part. Then we have Biomarkers … :slight_smile:


(Michael Gurley) #6

For biomarker coverage, please take a look at the CAP Cancer Protocols:

Let us know if the CAP Cancer Protocols cover your biomarkers of interest.
We hope (eventually) to get the CAP biomarker coverage via the Nebraska Lexicon: an effort to normalize the CAP Cancer Protocols to standardized vocabularies like SNOMED and LOINC. See here:
https://www.unmc.edu/pathology/informatics/tdc


(JD Liddil) #7

CAP does and I feel along with the genomics work being done we can keep pace with the ever changing immunotherapy landscape.


(Michael Gurley) #8

@jliddil1
FYI:

Go get the latest Registry Manual from STandards for Oncology Registry Entry (STORE)

https://www.facs.org/quality-programs/cancer/ncdb/registrymanuals/cocmanuals

Go to ‘AJCC TNM Clin Stage Group’. Look at the ‘Coding Instructions’. You will see a table that includes ‘IA3’. Looks like this is what we need to source.


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