We are currently setting up OMOP CDM at our site and am slowly trying to familiarize myself with how studies are conducted and what methods are utilized etc.
Am not from a healthcare background but trying to pick up the required skills for CDM-based research by reading OMOP CDM related papers. Currently am reading the LEGEND-HTN paper and have few questions.
can help me with the below questions, please?
q1) I am quoting few lines from the paper - “LEGEND-HTN is …representing 4·9 million patients initiating monotherapy across nine databases from four countries, examining all pairwise comparisons between the five first-line drug classes against a panel of 55 health outcomes. This equates to 22 000 traditional observational studies”
May I know how does this equate to 22000 studies? Can anyone let me know how to arrive at this number? Its purely due to my limitation that I don’t understand this… Is it 9 (dbs)* 4 (countries)* 2 (pairwise) * 5 (first line drug classes) * 55 (health outcomes)?
But this comes to about 19800 only. Can help me how it 22000?
q2) Is it okay if I follow the same procedure (posting in the forum) to ask questions on OMOP-CDM related papers for educational purpose or should I only mail the authors? I felt posting it here can help others like me as well (who are new to OMOP CDM and healthcare)