We are working on modelling a data source on acute lymphoblastic leukemia. The immunophenotype is provided as T-cell ALL or B-cell ALL, as a generic classification without specifying the subtype (mature or precursor). In the attempt to map this variable in the condition domain, we have found as standard concepts 4173963 (B-cell acute lymphoblastic leukemia) and 4082462 (T-cell acute lymphoblastic leukemia). However, the synonyms associated to these concepts are more specific than the name of the concept itself. For instance, B-cell acute lymphoblastic leukemia subsumes only Burkitt cell leukemia.
Also both concepts are descendants of 134305 (Acute lymphoid leukemia), which subsumes other concepts such as 4082461 (Precursor B-cell acute lymphoblastic leukemia). We wonder if these concepts can be used in our context, since other generic non standard concepts as 42542141 (B-cell acute lymphoblastic leukemia) have 4173963 (B-cell acute lymphoblastic leukemia) as Non-standard to Standard map (OMOP), or if there is a more appropriate and generic way to map this variables. We’d really appreciate it if you could help us.
Many thanks in advance!