First Course Treatment

Vocabulary Users
1

Hi all,

I’m working on mapping data from a cancer registry into the OMOP Common Data Model. I’ve successfully identified specific fields for second course therapies (as shown in the attached image), but I’m trying to determine whether there are explicit fields for first course treatments, specifically for chemotherapy, radiation, surgery, or transplant.

While I’ve found some first course chemotherapy fields that explicitly indicate when chemotherapy was not administered, I’m looking for discrete fields that affirmatively indicate when chemotherapy—or other treatment modalities—were part of first course therapy.

I’m aware of several general fields referencing first course or (neo)adjuvant therapies, but I’m specifically looking for fields that clearly distinguish treatment modality during the first course—i.e., something analogous to the 2nd course structure, but for 1st course.

Any guidance would be appreciated!

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1 Like
2

Hi @arflierl:

We don’t have the concept of a “first” or “second” treatment, or any other numbered treatment. I also don’t know what “course” is. Is that the second dose in a cycle, or the second cycle, or the second line of therapy?

In OMOP, you just record the actual treatment at the day it was provided. You can also record the chemotherapy regimen in the EPISODE table. The fact that a line of treatment is second is self-evident from the fact that there was one before (the first).

What kind of data do you have in the registry?

3

Okay, I can make that work. First course treatment involves any treatment modalities used as part of the initial treatment plant, and has an end date related to different scenarios of disease progression, recurrence, or treatment failure. It can last a year or more until one of these scenarios presents itself.