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DAY 2 REPORT: #OHDSICOVID19 Study-A-Thon

Day 2 Updates

Early Call: Video
Global Call: Video
Wrap-Up Call: Video

• The biggest news of the day came during the morning call, as it was announced by Seng Chan You that there was a guide to the new release of COVID-19 data for international collaboration research. Please watch the early call for more details, or read this forum post. If you are interested in participating in the research, please apply here.

At OHDSI, we talk so much about collaboration and open science, and this is such a critical example of those benefits. Thank you to Chan, Rae Woong Park, and everybody in South Korea who worked together to make a national data resource available to enhance the chances of generating meaningful real-world evidence during this global pandemic.

Here are just a few of the team updates so far, but please watch the global call for even more about ongoing progress.

• The estimation team is looking into the effects of several medicines being used in various COVID-19 trials. Protocols are being finalized, with the hopes of analytical packages being distributed within the network later Friday.

• The characterization team continues interesting conversation around how best to characterize a population of hospitalized COVID-19 patients (what symptoms should we be seeking for those who aren’t clearly diagnosed with COVID?). Other challenges have been discussed and addressed, and the team did a great job developing definitions and passing them to the phenotype team.

• The prediction group continues to create definitions for the target population of at-risk patients and the outcomes being studied. Valuable discussions have led to different sensitivity analysis outcome definitions that are being developed. With phenotypes coming (see next note), the group is hard at work developing studies that can provide much-needed insight into healthcare decision-making.

• The phenotype development team continues its work to produce common definitions to share with the afore-mentioned teams for use in upcoming network studies (both this weekend and beyond). By the end of the night, they hope to have all phenotypes necessary for target comparators and outcome cohorts available in a package. It’s motivating to the group to see how its work can impact so many fellow collaborators.

Beyond the update, there was another good Q&A segment at the end of the global call that opened more interesting discussion.

Thank you to all collaborators who continue to power through all the discussions and tasks necessary to go through this particular journey, which will set the foundation of a much longer research journey towards generating real-world evidence that can inform the COVID-19 response. The energy and passion within all the teams is inspiring!

Check back later tonight for more updates and video of the final Day 2 call. To read the Day 1 report, please click here.

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