This recent AHRQ posting looks like a potential good one for OHDSI:
Despite the growing interest and rapid pace of recent achievements, not much is known with a high degree of confidence about the prevalence of diagnostic failure in its various manifestations. This Funding Opportunity Announcement (FOA) solicits applications from research institutions and their investigators to conduct Health Services Research Projects (R01) to gain a better understanding of the complexity and incidence of diagnostic failure and its associated costs and harms.
When unnecessary diagnostic tests are ordered, there can be both a squandering of costly health care resources and a denial of the opportunity of receiving a timely diagnosis and appropriate treatment. More needs to be known about the conditions under which diagnostic tests are overused, underused, and appropriately used.
Given our scale, I think we’d have a good shot with the right analysis plan. Anyone else interested?