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Adjusting for general wellness decline

(Joshua Vogelstein) #1

In our analysis, we’d like to adjust for “general wellness decline”, for example, if somebody has been slowly dying over the last year, and caught COVID in the hospital, that seems like a very different situation than somebody who is very healthy, the same age, and caught COVID because she is a healthcare worker.

Are there any papers that describe how one might adjust for this, or why it is not worth it?

Many thanks, Joshua