OHDSI MEETINGS THIS WEEK
OHDSI Community Call - Tuesday at 12pm EThttps://meetings.webex.com/collabs/#/meetings/detail?uuid=M59X2V1U61WC9ASID2Z5N3UT95-D1JL&rnd=811649.9868221
CDM and Vocabulary WG - Tuesday at 1pm EThttps://jjconferencing.webex.com/mw3100/mywebex/default.do?service=1&main_url=%2Fmc3100%2Fe.do%3Fsiteurl%3Djjconferencing%26AT%3DMI%26EventID%3D594628767%26MTID%3Dma32e5ce14c744149f041412fc99040f1%26Host%3DQUhTSwAAAAR8_bMWcu3UJIUoSx6Dsi1wlRyeBFbZiHwpzM5RdtXUEd9EkPZnp_VKVWfI7L2rn716r0QSj9MFqtG6pLb1LVJE0%26FrameSet%3D2&siteurl=jjconferencing&nomenu=true
Population-Level Estimation (Western hemisphere) workgroup meeting - Thursday at 12pm EThttps://meetings.webex.com/collabs/#/meetings/detail?uuid=M3T9BZV9RSB6YNDM8WDDZMI19D-D1JL&rnd=229240.54296
Hadoop WG meeting - Friday at 11am EThttps://meet.lync.com/quintiles-quintilesims/mui.vanzandt/R8V4N3S9
GIS working group meeting - Monday (February 19th) at 10am ET
Simple, modern video meetings for the global workforce. Join from anywhere, including your desktop, browser, mobile device, or video room device.
ANNOUNCEMENTS
2018 OHDSI Symposium - SAVE THE DATE!
2018 OHDSI F2F: The 2018 F2F is set to take place on May 2-3rd at Columbia University Medical Center in New York. This year we’re going hold a study-a-thon! To learn more, check out @Patrick_Ryan ’s forum post: OHDSI Face-to-Face at Columbia May2-3: Community study-a-thon
OHDSI China Hack-a-thon - SAVE THE DATE Mark your calendars! The OHDSI China Hack-a-thon is officially set to take place on May 18th – 20th in Shanghai. More details to be posted soon.
COMMUNITY PUBLICATIONS
Gout drugs use and risk of cancer: A case-control study.
HC Yang, PAA Nguyen, M Islam, CW Huang, TN Poly, U Iqbal and YJ Li,
Joint, bone, spine : revue du rhumatisme , Feb 2018 07
Firm conclusion about whether short and long-term gout medications use has an impact on cancer risk remain inconclusive. The aim of this study was to investigate the association between gout drugs use and risk of cancer.We conducted a retrospective longitudinal population-based case-control study in Taiwan. Cases were identified all patients who were aged 20years or above, and had a first time diagnosis of cancers for the period between 2001 and 2011. Adjusted odds ratios (AORs) and 95% confidence intervals (CIs) were calculated by using conditional logistic regression.We examined 601,733 cases and 2,406,932 matched controls. The adjusted odd ratio for any gout drugs use and overall cancer risk was 1.007 (95% CI: 0.994-1.020). There was a significant risk of leukemia (AOR: 1.34, 95% CI: 1.20-1.50), endometrial cancer (AOR: 1.33, 95% CI: 1.12-1.57), non-Hodgkin's (AOR: 1.24, 95% CI: 1.13-1.35), female breast cancer (AOR: 1.21, 95% CI: 1.13-1.29), cervical cancer (AOR: 1.21, 95% CI: 1.07-1.37). However, no association was observed in male group (AOR: 0.97, 95% CI: 0.95-0.98) but female showed a significantly increased risk of cancer at any site (AOR: 1.107, 95% CI: 1.08-1.13).In summary, our results suggest that gout drugs increase risk of the most common cancers, particularly in leukemia, non-Hodgkin's, endometrial, breast and cervical cancer.
Clinical Information Systems Integration in New York City’s First Mobile Stroke Unit.
BR Kummer, MP Lerario, BB Navi, AC Ganzman, D Ribaudo, SA Mir, S Pishanidar, T Lekic, O Williams, H Kamel, RS Marshall, G Hripcsak, MSV Elkind and ME Fink,
Applied clinical informatics , 2018 01
Mobile stroke units (MSUs) reduce time to thrombolytic therapy in acute ischemic stroke. These units are widely used, but the clinical information systems underlying MSU operations are understudied.The first MSU on the East Coast of the United States was established at New York Presbyterian Hospital (NYP) in October 2016. We describe our program's 7-month pilot, focusing on the integration of our hospital's clinical information systems into our MSU to support patient care and research efforts.NYP's MSU was staffed by two paramedics, one radiology technologist, and a vascular neurologist. The unit was equipped with four laptop computers and networking infrastructure enabling all staff to access the hospital intranet and clinical applications during operating hours. A telephone-based registration procedure registered patients from the field into our admit/discharge/transfer system, which interfaced with the institutional electronic health record (EHR). We developed and implemented a computerized physician order entry set in our EHR with prefilled values to permit quick ordering of medications, imaging, and laboratory testing. We also developed and implemented a structured clinician note to facilitate care documentation and clinical data extraction.Our MSU began operating on October 3, 2016. As of April 27, 2017, the MSU transported 49 patients, of whom 16 received tissue plasminogen activator (t-PA). Zero technical problems impacting patient care were reported around registration, order entry, or intranet access. Two onboard network failures occurred, resulting in computed tomography scanner malfunctions, although no patients became ineligible for time-sensitive treatment as a result. Thirteen (26.5%) clinical notes contained at least one incomplete time field.The main technical challenges encountered during the integration of our hospital's clinical information systems into our MSU were onboard network failures and incomplete clinical documentation. Future studies are necessary to determine whether such integrative efforts improve MSU care quality, and which enhancements to information systems will optimize clinical care and research efforts.
