[OHDSI COVID-19] Review on the effect of ACE inhibitors and Angiotensin Receptor Blockers on COVID-19 incidence and complication rate

Hi everyone,

As posted by @CSung in Research questions that the OHDSI community can potentially answer to suport the COVID-19 response, there’s also a hypothesis that AT1R blockers / angiotensin 2 such as losartan or valsartan can have a beneficial/protective effect. Since these are common medicines for treatment of a.o. hypertension, there is a chance that we can see this effect in action if we can identify these subgroups. Is this something we can assess in the study-a-thon?

See https://doi.org/10.1002/ddr.21656 and there’s also a nice explainer video of the biochemistry which I have to look up,

Greetings,

Kees