@Nan, welcome to the OHDSI community, and thank you for your question. When encountering challenges with mapping concepts to the OMOP Common Data Model (CDM), it’s understandable to question how the model achieves its goal of standardization. Your concerns about using different concept_ids for the same value and the lack of consistent vocabularies within the OMOP database are valid. However, the OMOP CDM is designed to address these issues through several key principles.
Firstly, regarding the use of different concept_ids for the same value, the flexibility in assigning concept_ids allows for accommodating various vocabularies and local terminologies. While it may seem counterintuitive to have multiple identifiers for the same concept, this approach allows researchers to leverage their preferred vocabularies and ensures that diverse data sources can be harmonized into a common format. The goal is not strict uniformity but rather interoperability, enabling data sharing and collaboration across different studies and institutions.
To address the challenge of combining concepts from different vocabularies, the OMOP CDM provides tools and guidelines for mapping concepts to standardized vocabularies whenever possible. While it’s true that some concepts may not have direct mappings to the same vocabulary, efforts are made to harmonize similar concepts across vocabularies. Additionally, mappings can be supplemented with additional metadata to clarify the relationship between concepts from different sources.
Regarding the inconsistency in vocabularies within the OMOP database, this reflects the diversity of real-world healthcare data. Different institutions may use different coding systems based on their preferences, available resources, or specific clinical workflows. The OMOP CDM acknowledges this reality and provides mechanisms for integrating diverse data sources while maintaining semantic interoperability.
When sharing data with other OMOP models, it’s essential to document the mappings and transformations applied to ensure transparency and reproducibility. Data partners can exchange metadata about the vocabularies used, mappings performed, and any transformations applied to facilitate cross-study comparisons and analyses. Collaboration within the OHDSI community and adherence to best practices for data standardization further support data harmonization efforts across different OMOP instances.
In conclusion, while achieving complete standardization across all aspects of healthcare data is challenging, the OMOP CDM provides a framework for harmonizing diverse data sources and promoting interoperability. By embracing flexibility, transparency, and collaboration, the OMOP community strives to overcome the complexities of real-world data and enable robust observational health research.