Are there any updates on the progress on the TxPath tool?
At this moment we are exploring the old, ‘proper’ TxPath tool. First of all we want to understand what can be configured with the parameters.
By looking in the code, we came to the following descriptions of the parameters. It would be very helpful if someone could give us some feedback on this (@Frank @jon_duke?). Thanks in advance!
Study duration (days, default: 365)
A time frame starting at cohort inclusion of which a patient’s drug use/switches will be included in the results
Overlap period for drug switch events (days, default: 60)
If era’s of distinct drug use overlap, this is the number of days after which the current era of drug(s) use will induce a switch event to the drug (combination) of the new era
- Does this only affect assignation of switches (yes/no) or also the date that is assigned to a switch?
Calendar start/end dates (default: any date within study duration)
Additional absolute time constraint of what data should be used to generate the results
Minimum unit duration (days, default: 30)
Minimum number of days of continuous drug use required to allow a switch event
Minimum unit patient count (default: 10)
Minimum number of patients that must have the same drug switch event (or same initial drug) for it to be included in the results
Minimum adherence percentage (default: no minimum?)
Defined as 100% - gap percentage. Determines the maximum allowed gap percentage of a patient’s drug use for it to be considered valid (gap percentage = (average drug gap / average drug treatment duration) *100).
- Are average drug treatment duration and average drug gap based on consecutive era’s of identical drug use for each patient?