OHDSI Community Call 7Aug2018

[MauraBeaton]

Hi Everyone,

Here’s the agenda for Tuesday’s OHDSI call:

1. Introduction of OHDSI newcomers
2. Updates from the week

• OHDSI Network Research Studies: We’ll run through ongoing network research studies and ask study leads for the latest updates.
• Looking for presenters for August/September OHDSI calls
• Call for community feedback on:
  Guidelines for becoming a regional OHDSI chapter
  Guidelines for starting an OHDSI working group

3. Update - @clairblacketer will give us an overview of CDMv6.0
4. Presentation - @Patrick_Ryan will present on Applying OHDSI tools for large-scale analysis for comparative effectiveness: Clinical use case for Type 2 diabetes treatments

They certainly give very strange names to diseases.

• Plato

UPCOMING COLLABORATION OPPORTUNITIES

Upcoming Grant Deadlines
Immune Mechanisms at the Maternal-Fetal Interface (R01 Clinical Trial Optional)
https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-18-023.html
Application Deadline: October 4th

NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
https://grants.nih.gov/grants/guide/pa-files/PA-18-484.html
Application Deadline: October 5th

The Role of Epitranscriptomics in Development and Disease (R21 - Clinical Trial Not Allowed)
https://grants.nih.gov/grants/guide/pa-files/PAR-18-831.html
Application Deadline: November 7th

Investigator Initiated Research in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)
https://grants.nih.gov/grants/guide/pa-files/PAR-18-844.html
Application Deadline: November 16th
LOI due 30 days prior to the application due date

Upcoming Conferences
Machine Leanring in Healthcare - August 17-18th in Stanford CA
http://mucmd.org/

ISPOR Asia-Pacific Conference - September 8-11th in Tokyo, Japan
https://www.ispor.org/Event/index/2018Tokyo

2018 ASA Biopharmaceutical Section Regulatory-Industry Statistics Workshop - September 12-14th in Washington DC
http://ww2.amstat.org/meetings/biopharmworkshop/2018/

The International Society for Quality in Health Care - International Conference - September 23-26th in Kuala Lumpur, Malaysia
https://isqua.org/Events/malaysia-2018

International Semantic Web Conference - October 8-12th in Monterey, CA
http://iswc2018.semanticweb.org/

HOW TO JOIN THE MEETING

Time: Every Tuesday from 12-1pm ET
Join the Webex: https://meetings.webex.com/collabs/#/meetings/detail?uuid=M59X2V1U61WC9ASID2Z5N3UT95-D1JL&rnd=96139.93090141252332153122111221214123212113121311311211
Join the call using VoIP
How to use the VoIP: http://wlc.webex.com/docs/job_aids/IntegratedVoIP_JA.pdf

OR

Join the call using the following teleconference details:
+1-415-655-0001 (US Toll)
Attendee Code: 199 982 907
Meeting details are also available on the wiki:
http://www.ohdsi.org/web/wiki/doku.php?id=projects:ohdsi_community

[SCYou (Seng Chan You)]

I cannot access to the OHDSI call. Does it happen only to me?

[MauraBeaton]

Thanks everyone for joining today’s OHDSI call. A link to today’s recording is available here: https://drive.google.com/file/d/1zhoNbg49x1n06CQCT1j9KfsTHGgCCxVa/view?usp=sharing

A link to the paper Patrick discussed is available here:
https://onlinelibrary.wiley.com/doi/full/10.1111/dom.13424

Details about the upcoming CDMv6 release is posted here:

CDM v6.0 Roadmap

Hi All, As I discussed on the OHDSI call, here is the CDM v6.0 roadmap: Aug 2018 Finalize the v6.0 DDL SQL Script a. All change currently considered in the release are listed in the Github project Any additional changes to the CDM structure to be considered need to be in by Aug 24, 2018 a. These would be smaller changes like changing column names to be more consistent, updating ids to bigint, etc. b. Post an issue and if there is consensus they will be added c. If need be we can have an …

If you’d like to help @clairblacketer test the new version, you can let her know here:

CDM v6.0 Testers Needed

Dear OHDSI Community - As Maura alluded to in the agenda for the 8/7 call, we will be discussing CDM v6.0. Since this is a large release I will need help testing the DDL and constraints of each dialect. If you are interested, please reply to this post and I will put your name on the list. Testing will take place between 9/1/2018 and 9/21/2018. It helps to have more than one site testing so even if someone has already volunteered, please don’t hesitate to put your hand up! Dialect | Test Site…

And if you haven’t uploaded your abstract for the 2018 collaborator showcase, the deadline to submit is 5pm Today!!
https://www.ohdsi.org/collaborator-showcase/

[Rijnbeek (Peter Rijnbeek)]

Hi all,

I could not join the call yesterday but was able to watch the recording during my flight and I must say this was time well spend. I could not resist to post a reply…

@Patrick_Ryan i really enjoyed your presentation and I think we should not under estimate how unique the followed approach is: sharing all results in an interactive way should become the new standard. I therefore think that this study needs a bigger stage, it is really crazy that this study was presented only as a poster presentation. It is a great example on how we in OHDSI define transparent and reproducible research.

I would therefore like to make others, including European regulators, aware of this study and the power the CDM and all the great opportunities the framework and tools have to offer. I was wondering should we not push some great talks, like this one from Patrick, to the YouTube channel (or maybe all Tuesday meetings)? I know we have the Webex but that requires a tool to run etc etc. I also think we should be more proud on our website etc (the American way ).

Some other thoughts:

1. Do we foresee a future where others can upload the results of for example this study so we take this one step further: really dynamic up-to-date study results? In the PLP group we are working on this idea for prediction and especially external validation, but will we make this the standard for the future?

2. I saw in the presentation the (to me) cryptic name of the repository and shinyApp link. I am sure there is logic in this name, drug-comparator-outcome, something like that? Are we thinking of standardising this or do we actually prefer “Observe4D” in this case?

3. I also like the idea of @jon_duke to add annotation and discussion to make it even more interactive and dynamic. Not sure this can be done in Shiny but maybe embedded in another web-page with some threading functionality as seen for new articles etc.

@clairblacketer great work on how you are managing the CDM v6!

Peter