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Concept set for HIG codes for COVID research

I’m working with some researchers who are interested in studying the use of HIG in COVID-19 patients. The literature is a bit sparse on what codes are being used to pull these therapies.

My colleague pulled together this source table:

HIG CPT HCPCS
Unlisted immune globulin 90399
IG, human, intramuscular use 90281 J1560*
IgIV, human, intravenous use 90283 J1460*, J1566, J1599
Immune globulin (SCIg), human, for use in subcutaneous infusions (100mg) 90284
Injection, immune globulin (Cuvitru), 100 mg J1555
Injection, immune globulin (xembify), 100 mg J1558
Injection, immune globulin (Bivigam), 500 mg J1556
Injection, immune globulin/hyaluronidase, 100 mg immuneglobulin J1575
Injection, immune globulin (Vivaglobin), 100 mg J1562
Injection, immune globulin (Hizentra), 100 mg J1559
Injection, immune globulin, (Gammaplex), intravenous, nonlyophilized (e.g., liquid), 500 mg J1557
Injection, immune globulin (Privigen), intravenous, nonlyophilized (e.g., liquid), 500 mg J1459
Injection, immune globulin, (Gammagard liquid), nonlyophilized, (e.g., liquid), 500 mg J1469
Injection, immune globulin, (Gamunex/Gamunex-C/Gammaked), nonlyophilized (e.g., liquid), 500 mg J1561
Injection, immune globulin, (Octagam), intravenous, nonlyophilized (e.g., liquid), 500 mg J1568
Injection, immune globulin, (Flebogamma/Flebogamma Dif), intravenous, nonlyophilized (e.g., liquid), 500 mg J1572
Rh immune globulin (RhoGAM) ordered G8809

I’ve looked up the corresponding standards but I’m punching above my weight here. Not entirely sure what’s really being used in practice.

Is there anyone out there who’s got a point of view on this? Maybe even has a concept set already built? :wink: (@mattspotnitz @aostropolets @cukarthik @Gowtham_Rao @Azza_Shoaibi @Daniel_Prieto @danielmorales)

Hi @krfeeney, I haven’t built a concept set on this but can have a look at yours. I would recommend removing the RhoGAM concept (G8809) for now.

All these are non-standard drug. What you should be doing is taking RxNorm/CVX ingredients and building your concept set off of it. immune globulin in CVX and immunoglobulin G in RxNorm should do the trick.

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